CD285 antibody (Alexa Fluor 647)

Catalog No. ABIN2657161

The Mouse Monoclonal anti- antibody has been validated for ICFC. It is suitable to detect in samples from Mouse.

Quick Overview for CD285 antibody (Alexa Fluor 647) (ABIN2657161)

Target: CD285

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: Alexa Fluor 647

Application: Intracellular Flow Cytometry (ICFC)

Clone: ACT5

Product Details

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details

Target: CD285

Background: CD285, also known as TLR5, is a 98 kD pattern recognition receptor that binds to bacterial flagellin. It is expressed on dendritic cells, classical monocytes and mucosal epithelial cells and is involved in activation of TLR5 induced NF-κB mediated activation of inflammatory-related target genes. Mutations in the TLR5 gene have been linked with susceptibility to systemic lupus erythematosus and Legionnaire's disease.